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ACCUPRIL 5MG TAB 30

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ACCUPRIL®

Quinapril hydrochloride


Consumer Medicine Information

What is in this leaflet

This leaflet answers some common questions about Accupril.

It does not contain all the available information.

It does not take the place of talking to your doctor or pharmacist.

All medicines have risks and benefits. Your doctor has weighed the risks of you taking Accupril against the benefits they expect it will have for you.

If you have any concerns about taking this medicine, ask your doctor or pharmacist.

Keep this leaflet with your Accupril tablets. You may need to read it again.

What Accupril is used for

Accupril is used to lower high blood pressure (hypertension). It is also used to treat heart failure.

Hypertension 
Accupril is used to lower high blood pressure (hypertension). Everyone has blood pressure. This pressure helps get your blood all around your body. Your blood pressure may be different at different times of the day, depending on how busy or worried you are. You have hypertension (high blood pressure) when your blood pressure stays higher than is needed, even when you are calm and relaxed.

There are usually no symptoms of hypertension. The only way of knowing that you have hypertension is to have your blood pressure checked on a regular basis. If high blood pressure is not treated it can lead to serious health problems, including stroke, heart disease and kidney failure.

Heart Failure 
Heart failure means that the heart muscle is weak and cannot pump blood strongly enough to supply all the blood needed throughout the body. Heart failure is not the same as heart attack and does not mean that the heart stops. Heart failure may start off with no symptoms, but as the condition progresses, patients may feel short of breath or may get tired easily after light physical activity such as walking. Some patients may wake up short of breath at night. Fluid may collect in different parts of the body, often first noticed as swollen ankles and feet.

How Accupril works

Accupril works by widening your blood vessels, which reduces pressure in the vessels, making it easier for your heart to pump blood around your body. This helps increase the supply of oxygen to your heart, so that when you place extra demands on your heart, such as during exercise, your heart may cope better and you may not get short of breath as easily.

Accupril belongs to a group of medicines called angiotensin converting enzyme (ACE) inhibitors.

Your doctor may have prescribed Accupril for another reason.

Ask your doctor if you have any questions about why Accupril has been prescribed for you.

Accupril is not addictive.

This medicine is available only with a doctor's prescription.

Use in Children

The safety and effectiveness of Accupril in children have not been established.

Before you take Accupril

When you must not take it

Do not take Accupril if:

  • you have an allergy to Accupril or any other medicine containing quinapril, or any of the ingredients listed at the end of this leaflet
  • you have taken any other 'ACE inhibitor' medicine before, which caused your face, lips, tongue, throat, hands or feet to swell up, or made it hard for you to breathe
  • you or your family have a history of swelling of the face, lips, tongue, throat, hands or feet for no apparent reason.

Symptoms of an allergic reaction may include skin rash, itchiness, shortness of breath, swelling of the face, lips or tongue, muscle pain or tenderness or joint pain.

If you have had an allergic reaction to an ACE inhibitor before, you may be allergic to Accupril.

Use of ACE inhibitors have been associated with Syndrome of Inappropriate Anti-diuretic Hormone (SIADH) and subsequent low blood sodium levels.

Your doctor may also wish to do a blood test to monitor your sodium levels to ensure they are within normal limits. In the elderly and other at risk patients sodium levels may be monitored more frequently.

Do not take Accupril if:

  • you have kidney problems or a condition called 'renal artery stenosis'
  • you have regular dialysis for blood filtration.

You may experience an allergic reaction.

Do not take Accupril if you are currently taking a blood pressure lowering medicine containing aliskiren or with medicines known as angiotensin receptor blockers (ARB) or other ACE inhibitors and you have the following conditions:

  • diabetes
  • kidney problems
  • high levels of potassium in your blood
  • congestive heart failure.

You may experience severe side effects.

Do not take Accupril if you are pregnant or breastfeeding. Accupril may enter your womb or it may pass into the breast milk and there is the possibility that your baby may be affected.

Do not take Accupril after the expiry date printed on the pack or if the packaging is torn or shows signs of tampering.

If you are not sure whether you should start taking Accupril, talk to your doctor.

Before you start to take it

Tell your doctor if you have allergies to:

  • any other medicines
  • any other substances, such as foods, preservatives or dyes.

Tell your doctor if you have or have had any medical conditions, especially the following:

  • kidney problems, or are having dialysis
  • liver problems
  • heart problems
  • low blood pressure, which you may notice as dizziness or light-headedness
  • diabetes
  • high levels of potassium in your blood.

You must also tell your doctor if you:

  • are following a very low salt diet
  • are about to receive desensitisation therapy for an allergy
  • are about to undergo dialysis or lipoprotein apheresis
  • are about to have surgery or a general anaesthetic
  • plan to become pregnant or breastfeed.

If you have not told your doctor about any of the above, tell them before you start taking Accupril.

Taking other medicines

Tell your doctor or pharmacist if you are taking any other medicines, including:

  • all prescription medicines
  • all medicines, vitamins, herbal supplements or natural therapies you buy without a prescription from a pharmacy, supermarket, naturopath or health food shop.

Some medicines may be affected by Accupril or may affect how well it works. You may need different amounts of your medicines, or you may need to take different medicines. Your doctor will advise you.

Tell your doctor or pharmacist if you are taking any of the following:

  • other medicines used to treat high blood pressure
  • other medicines that work in a similar fashion to ACE Inhibitors, such as Angiotensin Receptor Blockers (these are used to treat high blood pressure and/or heart failure).
  • diuretics, also known as fluid or water tablets
  • non-steroidal anti-inflammatory drugs (NSAIDs) or Cox 2 inhibiting medicines used to relieve pain, swelling and other symptoms of inflammation, including arthritis
  • potassium supplements or potassium-containing salt substitutes
  • lithium, a medicine used to treat mood swings and some types of depression
  • tetracycline antibiotics
  • trimethoprim or trimethoprim/sulfamethoxazole, medicines used to treat bacterial infections.

Tell your doctor if you are taking any of the following blood pressure lowering medicines:

  • angiotensin II receptor blocker (ARB)
  • aliskiren.

For some patients, Accupril should not be taken in combination with these medicines.

Your doctor may check your kidney function, blood pressure and the amount of electrolytes (e.g. potassium) in your blood at regular intervals.

Tell your doctor if you are taking any of the following medicines:

  • mTOR inhibitors (e.g. temsirolimus), used in the treatment of kidney cancer
  • DPP-IV inhibitors (e.g. vildagliptin), used in the treatment of diabetes.
  • NEP inhibitors (e.g. sacubitril/valsartan), used in the treatment of congestive heart failure.

Taking Accupril in combination with these medicines may increase your risk of having an allergic reaction.

If you are not sure if you are taking any of the medicines mentioned in this leaflet, check with your doctor or pharmacist.

Your doctor and pharmacist may have more information on medicines to be careful with or avoid while taking Accupril.

How to take Accupril

Follow all directions given to you by your doctor or pharmacist carefully. They may differ from the information contained in this leaflet.

If you do not understand the instructions on the box, ask your doctor or pharmacist for help.

How much to take

Your doctor or pharmacist will tell you how many tablets you will need to take each day. This depends on your condition and whether or not you are taking any other medicines.

For high blood pressure 
For most patients, not on diuretics, the usual starting dose is 5 mg to 10 mg taken once a day. The dose may need to be increased depending on your blood pressure at an interval of 4 weeks. Most patients take between 10 mg and 40 mg each day.

This dose may be taken once a day or divided into two equal doses per day (one in the morning and one at night).

For heart failure 
The usual starting dose is 5 mg taken once a day. In most patients, effective doses are between 10 mg and 20 mg a day. Your doctor will advise whether the dose is to be taken as a single dose or as two separate doses (one in the morning and one at night).

How to take it

Swallow Accupril whole with a full glass of water.

Do not chew the tablets.

When to take it

Take Accupril at about the same time each day. Taking your tablets at the same time each day will have the best effect. It will also help you remember when to take the tablets.

Take Accupril before meals. Food with a high fat content may interfere with the absorption of Accupril.

How long to take it

Continue taking your medicine for as long as your doctor tells you. Accupril helps control your condition, but does not cure it. It is important to keep taking your medicine every day even if you feel well.

If you forget to take it

If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to.

Otherwise, take it as soon as you remember and then go back to taking your medicine as you would normally.

Do not take a double dose to make up for the dose that you missed. This may increase the chance of you getting an unwanted side effect.

If you are not sure what to do, ask your doctor or pharmacist.

If you have trouble remembering to take your medicine, ask your pharmacist for some hints.

If you take too much (overdose)

Immediately telephone your doctor or the Australian Poisons Information Centre (telephone 13 11 26), or the New Zealand National Poisons Information Centre (telephone 0800 POISON or 0800 764 766), or go to Accident and Emergency at the nearest hospital, if you think that you or anyone else may have taken too much Accupril.

Do this even if there are no signs of discomfort or poisoning.

You may need urgent medical attention.

If you take too much Accupril, you may feel light-headed, dizzy or you may faint.

While you are taking Accupril

Things you must do

If you are about to be started on any new medicine, remind your doctor, dentist or pharmacist that you are taking Accupril.

Make sure you drink enough water during exercise and hot weather when you are taking Accupril, especially if you sweat a lot. If you do not drink enough water while taking Accupril, you may feel faint, light-headed or sick. This is because your blood pressure is dropping suddenly. If you continue to feel unwell, tell your doctor.

Tell your doctor if you have excess vomiting or diarrhoea while taking Accupril. You may lose too much water and salt and your blood pressure may drop too much.

Tell your doctor immediately if you feel light-headed or dizzy after taking your first dose of Accupril, or when your dose is increased. This is especially important if you are taking Accupril for heart failure.

If you are going to have surgery that needs a general anaesthetic, tell your doctor or dentist that you are taking Accupril. Your blood pressure may drop suddenly.

If you become pregnant while taking Accupril, tell your doctor immediately.

If you are about to have any blood tests, tell your doctor that you are taking Accupril. Accupril may interfere with the results of some tests as it can result in sodium blood levels that are lower than the normal limits

Have your blood pressure checked when your doctor says, to make sure Accupril is working.

Go to your doctor regularly for a check-up. Your doctor may occasionally do a blood test to check your potassium levels and see how your kidneys are working.

Things you must not do

Do not give Accupril to anyone else, even if they have the same condition as you.

Do not take Accupril to treat any other complaints unless your doctor or pharmacist tells you to.

Do not stop taking Accupril, or change the dosage, without checking with your doctor.

Things to be careful of

If you feel light-headed, dizzy or faint when getting out of bed or standing up, get up slowly. Standing up slowly, especially when you get up from bed or chairs, will help your body get used to the change in position and blood pressure. If this problem continues or gets worse, talk to your doctor.

Be careful driving or operating machinery until you know how Accupril affects you. As with other ACE inhibitor medicines, Accupril may cause dizziness, light-headedness or tiredness in some people. Make sure you know how you react to Accupril before you drive a car, operate machinery, or do anything else that could be dangerous if you are dizzy or light-headed. If this occurs do not drive. If you drink alcohol, dizziness or light-headedness may be worse.

Things that would be helpful for your blood pressure or heart failure

Some self help measures suggested below may help your condition.

Talk to your doctor or pharmacist about these measures and for more information.

Alcohol 
Your doctor may advise you to limit your alcohol intake.

Weight 
Your doctor may suggest losing some weight to help lower your blood pressure and help lessen the amount of work your heart has to do. Some people may need a dietician's help to lose weight.

Diet 
Eat a healthy diet which includes plenty of fresh vegetables, fruit, bread (preferably wholegrain), cereals and fish. Also eat less sugar and fat (especially saturated fat) which includes sausages, fatty meats, full cream dairy products, biscuits, cakes, pastries, chocolates, chips and coconut. Monounsaturated and polyunsaturated fats from olive oil, canola oil, avocado and nuts are beneficial in small quantities.

Salt 
Your doctor may advise you to watch the amount of salt in your diet. To reduce your salt intake you should avoid using salt in cooking or at the table and avoid cooked or processed foods containing high sodium (salt) levels.

Exercise 
Regular exercise, maintained over the long term, helps to reduce blood pressure and helps get the heart fitter. Regular exercise also improves your blood cholesterol levels, helps reduce your weight and stress levels, and improves your sleep, mood and ability to concentrate. However, it is important not to overdo it. Before starting any exercise, ask your doctor about the best kind of programme for you.

Smoking 
Your doctor may advise you to stop smoking or at least cut down. Ask your doctor or pharmacist for further information and advice.

Side effects

Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Accupril.

Accupril helps most people with high blood pressure and heart failure, but it may have unwanted side effects in a few people.

All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.

It can be difficult to tell whether side effects are the result of taking Accupril, effects of your condition or side effects of other medicines you may be taking. For this reason it is important to tell your doctor of any change in your condition.

If you are over 65 years of age you may have an increased chance of getting side effects.

Do not be alarmed by the list of side effects. You may not experience any of them.

Ask your doctor or pharmacist to answer any questions you may have.

Tell your doctor if...

Ask your doctor or pharmacist for advice if you notice any of the following and they worry you:

  • feeling light-headed, dizzy or faint
  • dry cough
  • headache
  • feeling sick (nausea) or vomiting
  • stomach pain
  • diarrhoea
  • constipation
  • unusual tiredness or weakness, fatigue
  • feeling drowsy or sleepy during the day
  • hair loss or thinning
  • dry mouth or throat
  • taste disturbances or loss of taste
  • confusion or nervousness
  • back pain
  • rash
  • difficulty in getting or maintaining an erection.

These side effects are usually mild. All side effects should be reported to a health professional.

Tell your doctor as soon as possible if...

Tell your doctor as soon as possible if you notice any of the following:

  • disturbed vision
  • symptoms of sunburn (such as redness, itching, swelling, blistering) which may occur more quickly than normal
  • itchy, raised or red skin rash
  • signs of worrying or frequent infections such as fever, severe chills, sore throat or mouth ulcers
  • aching, tender or weak joints or muscles not caused by exercise
  • feelings of deep sadness and unworthiness (depression)
  • severe upper stomach pain, often with nausea and vomiting
  • passing little or no urine
  • bleeding or bruising more easily than normal.

The above list includes serious side effects that may require medical attention. Serious side effects are rare.

Go to hospital if...

Tell your doctor immediately or go to Accident and Emergency at your nearest hospital, if you notice any of the following:

  • fainting within a few hours of taking a dose
  • fast or irregular heart beat
  • shortness of breath or tightness in the chest
  • sudden onset of stomach pains or cramps with or without nausea or vomiting
  • severe flaking or peeling of the skin
  • severe blisters and bleeding in the lips, eyes, mouth, nose and genitals
  • chest pain.

These are very serious side effects. You may need urgent medical attention or hospitalisation. These side effects are very rare.

Stop taking Accupril and tell your doctor immediately or go to Accident and Emergency at your nearest hospital if you notice the following:

  • swelling of the face, lips, mouth, tongue or throat which may cause difficulty in swallowing or breathing.

Tell your doctor or pharmacist if you notice anything that is making you feel unwell.

Other side effects not listed above may also occur in some people.

After taking Accupril

Storage

Keep your tablets in the box until it is time to take them.

If you take the tablets out of the box they may not keep well.

Keep your tablets in a cool dry place where the temperature stays below 25 °C.

Do not store Accupril or any other medicine in the bathroom or near a sink.

Do not leave it on a windowsill or in the car on hot days.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Disposal

If your doctor or pharmacist tells you to stop taking Accupril or the tablets have passed their expiry date, ask your pharmacist what to do with any that are left over.

Product description

What it looks like

Accupril tablets come in three strengths and each has a different appearance:

Accupril 5 mg - Reddish-brown, oval, biconvex, film-coated tablet with bisecting score on both sides and debossing "5" on both sides in opposite direction.

Accupril 10 mg - Reddish-brown, triangular, biconvex film-coated tablet with bisecting score on both sides and debossing "10" on one side.

Accupril 20 mg - Reddish-brown, round, biconvex film-coated tablet, with bisecting score on both sides and debossing "20" on one side.

A box of Accupril contains 30 tablets.

Ingredients

Active ingredient:

  • Accupril 5 mg - 5 mg quinapril (as the hydrochloride)
  • Accupril 10 mg - 10 mg quinapril (as the hydrochloride)
  • Accupril 20 mg - 20 mg quinapril (as the hydrochloride)

Other ingredients:

  • magnesium carbonate hydrate
  • lactose monohydrate
  • gelatin
  • crospovidone
  • magnesium stearate
  • candelilla wax
  • iron oxide red
  • titanium dioxide.

Accupril does not contain sucrose, gluten, tartrazine or any other azo dyes.

Supplier

Accupril is supplied in Australia by:

Pfizer Australia Pty Ltd
ABN 50 008 422 348
38-42 Wharf Road
West Ryde NSW 2114
Australia
Toll Free Number: 1800 675 229

Accupril is supplied in New Zealand by:

Pfizer New Zealand Limited
PO Box 3998
Auckland
New Zealand
Toll Free Number: 0800 736 363

Australian Registration Numbers

Accupril 5 mg - AUST R 40926

Accupril 10 mg - AUST R 40928

Accupril 20 mg - AUST R 40930

This leaflet was prepared April 2017.

© Pfizer Australia Pty Ltd 2015.

® Registered Trademark.

Delivery info

Please note that Public Holidays will add on extra delivery time for orders

Superpharmacy Orders will be packaged in plain, impervious packaging that is unmarked for security and privacy reasons. Orders will be dispatched as soon as possible once payment is received. For Orders containing prescription items please see the prescription processing procedure. Orders for both prescription and non-prescription items will most likely be delivered separately, unless otherwise directed, where we do not hold the prescription paperwork at the time of placing the order.

Australia Wide shipment details

On all Australian orders less than $50 in value (and under 3kgs) we have a flat rate shipping fee of $8.95.

All Australian orders $50 or more in value (and under 3kgs) will qualify for FREE DELIVERY.

Any orders over 3kgs will have our Online Team be in contact with further information regarding shipping.

All orders of Prescription items will receive FREE DELIVERY regardless of order value.

All orders of compounding items will qualify for FREE DELIVERY.

PRESCRIPTION PROCESSING PROCEDURE

Orders for prescription items can only be processed once we physically receive your prescription paperwork. Prescription product orders will be dispensed and dispatched on the business day the prescription or valid repeat authorisation is received at the SUPERPHARMACY registered premises.Please send your prescription paperwork to the appropriate store

NSW, NT and TAS:  SUPERPHARMACY PO Box 1877 Hornsby Westfield 1635

QLD: Superpharmacy 187 Days Road, Grange QLD 4051

SA: Superpharmacy 41 Hindley Street, Adelaide SA 5000

VIC: Superpharmacy 92 Lygon Street, East Brunswick VIC 3057

WA: Superpharmacy 259 Walcott Street, North Perth WA 6006

Ensure to allow sufficient time for the delivery of your prescription or repeat authorisation paperwork to us and the subsequent order delivery via our specialised delivery network. We recommend considering a total of up to 7 days for metro areas or 10 days in remote areas. If we do not already hold your prescription paperwork, it will be necessary for you to send the prescription paperwork to us before we can dispatch your order. Please also allow appropriate time for the prescription to reach us and for the order to be sent back so as to avoid running out of your ongoing prescription medicine.

We partner with well-known and trusted delivery services to minimise delivery times. These include:

  • Our own personal delivery driver
  • StarTrack
  • Auspost
  • Local delivery couriers

The end goal is to get your order to you as fast and as securely as possible.

Details of the delivery process and conditions are included in the Superpharmacy Terms and Conditions found here

Superpharmacy will dispatch most orders within ONE business day on Monday to Friday assuming all items are in stock. All other orders will be dispatched as quickly as possible thereafter. It may be necessary for some orders to be shipped in more than one box from different distribution sites and therefore you may obtain these parcels at different times. We will notify you via email if there is a delay in the delivery of an item in your Order and what action we have taken. Please contact our Customer Service on 13004MEDICINE during business hours if you would like an alternative product or arrangement. Order processing and delivery times may vary in peak times with special arrangements during peak volume times such as Christmas, Mother's Day and Superpharmacy promotions. Contact our Customer Service on 1300 4MEDICINE during business hours or email customerservice@superpharmacy.com.au for more information.

Postage and handling for international orders

We do not currently deliver outside of Australia 

Returns & exchanges

Returns Policy

All enquiries regarding online product Returns or Refunds should be made through our Customer Service Team by telephone at 13004MEDICINE (1300 463 342)‚Äč

The SUPERPHARMACY Returns Policy applies to all purchases of Products using the Site and forms part of the terms and conditions. If you wish to return a Product in accordance with our Returns Policy, then you must:

(a) Check your Goods as soon as they are delivered to you in order to ensure that: (i) they are what you ordered; and (ii) they are not damaged or faulty.  The return of a Product must be authorised by the appointed Superpharmacy Customer Service Representative prior to taking any action to return the Product.

Damaged or Defective Goods

We will replace or refund (at our discretion) any items delivered to you that are damaged or defective at no charge.

Should you be eligible for a Product refund, it will be arranged as follows:

  • Upon making contact with the Customer Service Team, a Representative will work with you to resolve the issue, detailing the steps involved in the refund and any further information applicable.
  • Refunds will be handled by our Customer Service Team on an individual basis.

Should you be eligible for a Product replacement, it will be arranged as follows:

  • Upon making contact with the Customer Service Team, a representative will work with you to facilitate the easiest means of getting a replacement product delivered.
  • The Representative will dictate any further action required and supply the necessary information.
  • Product replacement timeframes will be detailed to you during these steps.

Incorrect Items Ordered

If you have ordered incorrect items, you have 7 days from date of order placement to notifiy our Customer Service Team. They will then facilitate the process of resolution. Please be aware there are certain factors listed below which must be met before a Product Return/Refund request can proceed.

  • Customer Service Team must be notified within 7 days.
  • Superpharmacy is required to receive the product back in unopened, original packaging that is in good condition (condition of product received decided at discretion of Representative)

Once a product it received back at a Superpharmacy premesis, and all previously listed conditions are met, the Customer Service Representative will be able to proceed with a refund or exchange request.

When you return a Product please ensure it is packed to avoid damage in transit. We highly recommend you photograph the Product inside the packing prior to sending.

Prescription Returns

Due to NSW Health Regulations, prescription items cannot be returned for refund.

The SUPERPHARMACY Returns Policy applies in addition to any other rights to which you may be entitled under the consumer guarantees provisions of the Australian Consumer Law.